In patients with myasthenia gravis, which treatment may become necessary during a crisis?

In patients with myasthenia gravis, a crisis can occur when there is a significant exacerbation of muscle weakness, particularly affecting respiratory muscles, which can lead to respiratory failure. During such a crisis, ventilator support may become necessary to assist with breathing and ensure adequate oxygenation until the patient stabilizes.

This treatment approach is critical because myasthenic crises can lead to severe complications, including respiratory arrest. Patients may require intubation and mechanical ventilation if they cannot maintain effective ventilation on their own. The focus during an acute crisis is to maintain respiratory function and stabilize the patient's condition.

While other treatment options may be relevant in different contexts, such as managing myasthenia gravis outside of a crisis or addressing secondary complications (like infections), they are not immediate necessities during an acute exacerbation. Invasive surgery is not a standard intervention for managing crises, long-term antibiotics are not indicated unless there is a concomitant infection, and psychiatric evaluation may be considered in some cases but is not an urgent requirement in the context of a myasthenic crisis.