What impact does stress and exercise have on symptoms of myasthenia gravis?

The correct choice reflects the understanding that stress and exercise can exacerbate the symptoms of myasthenia gravis, particularly worsening extremity weakness. Myasthenia gravis is an autoimmune disorder characterized by weakness in the skeletal muscles due to a breakdown in communication between nerves and muscles. During periods of stress or after vigorous exercise, the body demands additional muscular effort, which can further deplete the ability of weakened muscles to contract properly.

Individuals with myasthenia gravis often experience fluctuating muscle strength, and strenuous activity, which might normally improve strength in healthy individuals, can lead to increased fatigue and weakness in those affected by this condition. Stress can also amplify immune responses and potentially worsen the autoimmune process involved in myasthenia gravis. Therefore, understanding the nature of the disease and its response to physical and emotional stress is crucial for proper management and care.