What is the recommended tidal volume setting for lung protective ventilation in ARDS?

The recommended tidal volume setting for lung protective ventilation in patients with Acute Respiratory Distress Syndrome (ARDS) is 6-8 mL/kg of predicted body weight. This guideline is based on evidence that using lower tidal volumes helps to minimize ventilator-induced lung injury by reducing overdistension of alveoli and improving oxygenation without causing further damage.

The rationale behind this approach stems from studies that have shown that higher tidal volumes can lead to barotrauma and volutrauma, which exacerbate lung injury. By utilizing this lower tidal volume strategy, the focus shifts toward preventing further lung damage while still providing adequate ventilation and maintaining proper gas exchange. This method also aligns with the overall goals of ARDS management, which prioritize the protection of the lung parenchyma during ventilation.

The ranges of tidal volumes mentioned in the other options exceed the recommended levels and may increase the risk of complications associated with mechanical ventilation in ARDS patients.