What is the role of DMARDs in rheumatoid arthritis treatment?

The role of Disease-Modifying Anti-Rheumatic Drugs (DMARDs) in the treatment of rheumatoid arthritis is to modify disease progression. These medications work by targeting the underlying processes that contribute to the disease, rather than merely alleviating symptoms. This means they can slow the destructive nature of rheumatoid arthritis on the joints and potentially prevent long-term damage, which is critical for maintaining functionality and quality of life for patients.

While options such as immediate pain relief, reducing inflammation, and preventing joint surgeries are important aspects of arthritis management, they do not reflect the core purpose of DMARDs. DMARDs aim to alter the course of the disease by inhibiting inflammation and the immune response involved in rheumatoid arthritis. Consequently, the effectiveness of DMARDs lies in their ability to provide long-term benefits, such as reducing joint erosion and disability, rather than just addressing immediate symptoms or acting as a bridge to surgical interventions.