Which factor is NOT considered a prognostic sign during the first 48 hours of acute pancreatitis?

In the context of acute pancreatitis, prognostic factors are used to assess the severity of the condition and predict outcomes. A calcium level greater than 8 mg/dL is generally not considered a significant prognostic indicator during the initial 48 hours of the illness. Instead, hypocalcemia is often observed in the setting of acute pancreatitis, and lower calcium levels may be more pertinent to prognosis.

In contrast, a drop in hematocrit greater than 10% can indicate significant blood volume loss or hemorrhage, which is a critical prognostic cue. An increase in BUN greater than 5 mg/dL suggests dehydration or renal impairment, both of which adversely affect prognosis. Lastly, estimated fluid sequestration exceeding 6,000 mL indicates a severe inflammatory response and fluid collection, further correlating with worse outcomes. Therefore, among the listed factors, calcium levels being greater than 8 do not carry the same prognostic weight in the early hours of acute pancreatitis compared to the other indicators mentioned.