Which of the following is commonly given to prevent Wernicke's encephalopathy in alcoholics?

Vitamin B1, also known as thiamine, is commonly administered to prevent Wernicke's encephalopathy, particularly in individuals with chronic alcoholism. Wernicke's encephalopathy is a neurological condition that can occur due to thiamine deficiency, which is often observed in those with alcohol use disorder. Alcohol interferes with the absorption of thiamine in the gut and its conversion to its active form, leading to a deficiency even in the presence of adequate dietary intake.

The prevention approach involves giving thiamine, especially before administering glucose solutions, as glucose can exacerbate the symptoms of Wernicke's encephalopathy in a thiamine-deficient patient. Early intervention with thiamine can prevent the development of this serious condition, which is characterized by confusion, ataxia, and ophthalmoplegia.

Other vitamins listed in the choices—such as Vitamin C, folic acid, and Vitamin B12—are important for various bodily functions but do not directly prevent Wernicke's encephalopathy. Folate is often associated with macrocytic anemia and other deficiency conditions, while Vitamin B12 is essential for nerve function and red blood cell production. Vitamin C plays a vital role in immunity and skin health but does